Karen Fitzgerald's work has been widely exhibited in the United States. The Queens Museum of Art, Islip Art Museum, Rahr-West Museum, Madison Art Museum, Milwaukee Art Museum, Milwaukee Institute of Art & Design, the University of Arizona - Tucson and the United Nations in NY have featured her work in their active exhibition schedules. She received grants from the Queens Community Arts Fund, the Greenwall Foundation and the Women's Studio Workshop. Her work is in many private and public collections, including the Spencer Collection of the New York Public Library, Related Group, The Four Seasons Hotel, the Rienhart Collection of Germany, Montefiore Medical Center, NYU Langone Medical Center, and Memorial Sloan Kettering Cancer Center, NYC.
Fitzgerald has been working with the tondo form for almost 30 years. Her work is focused on an exploration and expression of energy; the essence of interconnection, wholeness and metaphysical purpose. Using a gilded ground of precious metals, whether copper, 23k, 18k, 21k or 12k gold, provides a distinctly "other-worldly" space. It evokes a universal space including our physical plane.